Noopept is a potent cognitive enhancer, thought to be one of the most effective and fast working brain supplements available, promoting a boost in concentration, mental clarity, memory and even supporting brain function. Making it an excellent Nootropic for productivity, prior to mentally demanding tasks.
What is Noopept?
Noopept (n-phenylacetyl-l-prolylglycine ethyl ester or GVS-111) is a Nootropic supplement designed to improve basic cognitive functions. It has proven
to be effective at enhancing the processes of your brain’s neurons, resulting in substantial
increases in mental energy, learning capacity, mental clarity and even improving your mood.
It was originally created in the 1970’s as a cognitive enhancer in the USSR, designed to boost the intellectual capacities of the astronauts. Patented in Russia and the USA in 1995, it was branded as Noopept, which is trademarked by it’s manufacturer JSC LEKKO Pharmaceuticals.
Noopept is sold in Russia and several neighboring countries and is used for it’s Nootropic effects. It’s popularity gained so much tread, it is now distributed worldwide.
This peptide compound has similar mechanisms of action to the Racetam family of Nootropics. However, it’s specific molecule structure makes it much more powerful and bio-available, making it 1000 times more potent than the first Nootropic ever created, Piracetam, producing similar effects with a smaller dose.
It’s effects are associated with increasing overall brain power, highly improving the ability to concentrate and focus, absorb and process new information (learn), promote clearer thinking and mental clarity, boost memory and even reduce symptoms of anxiety and depression.
Taken at the suggested dose, Noopept has no known negative side effects. However before trying Noopept, it can be helpful to understand how it works, examine the additional benefits, what to expect from user experiences and dosage guidelines.
How Does Noopept Work?
Noopept gets absorbed through the gastrointestinal tract. It than easily crosses the blood-brain barrier (reaches the brain) and begins to work. It reaches full concentration within 15-20 minutes due to it’s high bioavailability, which makes it the fastest acting Nootropic.
Once in the brain, Noopept simultaneously stimulates receptors that are associated with several neurotransmitters known to boost brain power. These are chemical messengers that communicate information from one neuron to another.
Noopept modulates AMPA and NDMA glutamate receptors and their pathways. It also stimulates the excretion of Acetylcholine (ACh) neurotransmitter, acting to boost CPG levels (cycloprolylglycine) in the brain.
Glutamate is a powerful neurotransmitter and the most important for normal brain function. It’s responsible for thought processes, perception and the formation of memory. Synaptic adjustments occur as Noopept binds to and activates these receptor sites, which increases the effects of Glutamate.
In addition, Noopept increases the circulation of Glutamate in the brain, allowing it to move between brain cells. This allows it to function more efficiently with receptors. It also promotes increases in the connections between the neurons which improves neural health.
Noopept also seems to modulate Acetylcholine (ACh) neurotransmission. This action is similar to Racetams. ACh is another important chemical messenger for learning and memory.
Noopept stimulates Dopamine and Serotonin receptor sites, contributing to anti-anxiety (anxiolytic) and mood boosting effects. Many people who take Noopept report that they are able to focus and concentrate better, while feeling more energized but mentally calm.
Finally, trials on rats who were given Noopept over a 28 day period resulted in raising levels of Nerve Growth Factor (NGF). This is a protein that regulates the reparation and maintenance of damaged brain cells and even encourages the growth of new brain cells and synapses that is vital for long-term memory.
Noopept Benefits & Effects
Noopept is thought to increase overall brain power and enhance the effects of mental clarity. As a cognitive enhancing supplement, it is indicated in many studies and from user reviews, that it can effectively increase learning abilities and memory formation and retrieval.
For some people, Noopept shows higher potential for positive cognitive effects than many other Nootropics since the benefits may be highly diverse and work much faster. Improvements in memory, alertness, concentration, analytical thinking, problem solving abilities, mental clarity, motivation and even reducing anxiety and depression are all possible with Noopept.
Noopept may improve memory and learning by assisting in managing signals and activity processed by the brain that form memories. This allows for better memory consolidation and retrieval and you may also have significant improvements in the ability to absorb more information, process it faster and recall it quicker.
If you often forget new information quickly, Noopept boost levels of Acetylcholine (ACh), a chemical messenger in the brain that transmits signals between the neurons and plays a role in encoding new memories. ACh, also contributes to your brains ability to form new connections which may improve problem solving skills and reasoning.
Noopept is believed to raise oxygen levels in the brain and the use of glucose by improving its metabolism. This is a sugar that is the brains main source of energy. This may be why many people who take Noopept report improvements in energy, mental clarity, focus, concentration and even sharper audio and visual perception.
In addition, Noopept is believed to develop new synapses that connect the left and right hemispheres of the brain, improving the communication. Commonly, most people are more dominant on one side, left is logical thinking, right is creative thought. This may result in better verbal communication.
Noopept is also noted to have neuroprotective properties that may act as an anti-oxidant, flushing excess calcium and other toxins that may cause damage to the brain.
Finally, Noopept has been reported to have anxiolytic (reducing anxiety) effects. Stress, insomnia, irritability and mood swings may improve with the use of this supplement. It is thought to stimulate Dopamine receptors and may also modulate Serotonin receptors which may contribute to less anxiousness and better moods.
Review on Noopept Common Experiences & Results
There are many user reports describing the experience and how they feel when taking Noopept. It is important to keep in mind that although there are common similar effects, that can vary from person to person.
There are many Noopept testimonials and reviews that consist of a wide range of benefits. While some people attest to Noopept being the best Nootropic supplement available, others may feel that other Nootropics have worked better for them.
Experimentation may be the answer since these differences in effects can be due to lack of sleep, medications, current individual neurotransmitter levels in the brain, tolerance levels and many other factors.
With that being said, users commonly report less brain fog when taking Noopept. This is a term that is sometimes used to describe a lack of mental clarity, trouble concentrating, not being able to remember information or low mental energy.
Users may notice big effects on memory. The ability to remember the smallest details with ease and even recall past events or places has been commonly reported with the use of Noopept.
Other significant experiences may be enhanced mental performance and mental clarity. You may notice the ability to think at a faster speed, thoughts may seem clearer and flow better and perception my be enhanced helping you to complete tasks with ease. You may also notice powerful effects in the ability to concentrate and focus without getting distracted.
Noopept may help some users be more socially outgoing and you may find it easier to engage in flowing, intellectual conversation.
Noopept is considered to be one of the very best Nootropic supplements available on the market. Although it can be used independently, some people commonly stack this supplement with other Nootropics to potentially increase the effectiveness and experience a wider range of cognitive effects that other Nootropics may provide simultaneously.
If you are a beginner and considering taking Noopept, it is recommended to not stack this product with other Nootropics to start. It has a high potency and it is best to first determine how the effects of this supplement, when taken on it’s own, may work for you.
However, a common combination or stack you may want to consider as a beginner, include taking Noopept with a high quality choline source such as Alpha GPC or CDP Citicoline. Noopept increases the uptake of Acetylcholine, a neurotransmitter that can produce many cognitive effects but requires choline to produce it.
For others who have already taken Noopept on it’s own and are considering stacking this Nootropic, common stacks reported by users include Noopept and Piracetam. These Nootropics may have synergistic effects, boosting memory and learning but working on different neurotransmitters, glutamate and acetylcholine, that may additionally produce other various cognitive effects.
In addition, you may want to consider stacking Noopept with any herbal or natural Nootropic to achieve proven, desired effects.
Does Noopept Have Side Effects?
Although Noopept is notable for it’s many powerful cognitive effects that it may produce, it appears to have few reported side effects or risks of dependency despite it’s potency. At the recommended dosage, studies attest to it’s safety.
Potential side effects are rare but if taken outside the recommended dosage, side effects can include dizziness, fatigue, nausea, restlessness and problems sleeping.
Irritability is the most common reported side effect of Noopept when taken consecutively for a long period of time. It is recommended to cycle this Nootropic if this occurs to allow your body to readjust.
Also, caution is advised when taking Noopept with other stimulants such as amphetamines. Evidence suggests that it may enhance their effects.
In addition, if you are pregnant or nursing, this supplement should be avoided for precaution purposes.
Noopept Dosage Guidelines
How much Noopept should you take? Noopept is very bio-available and potent so a small amount is sufficient. The recommended dosage is between 10 mg-30 mg per day.
For optimal effects, the suggested dosage is 10 mg taken twice a day, once in the morning and once in the afternoon. However, it is recommended to start at 5 mg-10 mg once daily and only increase the dosage once you are certain of the effects. Do not exceed 30 mg per day.
Noopept is suggested to be administered in small doses, several times a day to help maintain an effective level in the system due to it’s short but potent half-life. For faster absorption, you can place Noopept under your tongue (sublingual administration).
Noopept is sold in powder, tablet and capsule form. It is considered semi water soluble, so it may sink to the bottom of the glass when taken in powder form with water or juice. A better option may be capsules or tablets.