3,3′ Diindolylmethane also called DIM, is promoted to have key benefits in balancing hormones for both men and women, reducing inflammation and joint pain, alleviating symptoms of PMS and many other benefits.
What is Diindolylmethane?
Diindolylmethane (DIM) is used to improve a multitude of different health issues since it has shown varied medicinal effects.
It is a partial effect of the digestion of indole-3-carbinol (I3C) which is found in the brassica family of vegetables including broccoli, kale, cabbage, cauliflower and others. When indole-3-carbinol is broken down, it creates Diindolylmethane.
It is currently being researched for it’s potential effects on preventing the development and growth of cancer and has shown promising effects on breast, colorectal and uterine cancers. The FDA does not approve DIM supplementation for this purpose and more research is required to determine it’s effectiveness.
DIM is also thought to have anti-inflammatory, antibacterial, anti-angiogenesis and hormone balancing effects.
DIM contains phytonutrients (plant nutrients) that are believed to create healthy hormone balances for both men and women by balancing estrogen levels in the body.
Diindolylmethane (DIM) is suggested to help the results of drastic increases or decreases of estrogen levels and estrogen metabolism.
DIM is believed to reduce the level of 16-hydroxy estrogen and increase the creation of higher levels of 2-hydroxy estrogen which is the good estrogen.
When estrogen is broken down in the body, it creates either good or bad metabolites. Good or valuable metabolites act as anti-oxidants and protect the heart and brain from excessive damaging free radicals that increase with age and can cause diseases.
DIM also may be beneficial for people suffering from arthritis. It seems to have anti-inflammatory properties that help to reduce arthritic pain.
It is believed to effectively decrease inflammatory cytokine expression in animal tests and block inflammatory enzymes which may reduce inflammation and provide relief from pain. However, there is no evidence that suggest it can prevent arthritis.
Benefits of Diindolylmethane (DIM) For Men
For men, diindolylmethane can reduce symptoms of excessive breast tissue by potentially reducing estrogen dominance and increasing testosterone. DIM seems to create a hormone balance between them, which may lead to many other benefits for men.
The increase of testosterone is important in lowering the risk of cardiovascular disease and conditions. Low levels of testosterone can create lack of energy, erectile dysfunction, loss of muscle mass and low sex drive. Other symptoms can be hair loss and an increase in body fat that can effect overall physical performance.
Estrogen is present in every organ in both males and females. In men, testosterone is transformed into estrogen. If there is too much estrogen, it can can cause heart disease, prostate cancer and gynecomastia (enlarged breasts in men). DIM supplements are believed to be used for prevention of prostate related conditions.
A proper balance may also help the efficiency of cholesterol synthesis in the liver which may help to eliminate cholesterol from the body. Men have a greater risk for heart attacks, strokes and disease that may be caused by high cholesterol than women do, even though statistically there is a greater number of women with high cholesterol than men.
These supplements are also used as testosterone boosters. They may be a potential alternative to testosterone therapies since they may have less side effects that are commonly associated to these therapies.
Benefits of Diindolylmethane (DIM) For Women
For women, DIM is believed to balance estrogen and progesterone levels and that creates a healthy hormone balance. An imbalance is the most common problem in women over the age 35.
Women produce estrogen in the ovaries, fat cells and adrenal glands. When estrogen levels are imbalanced or dominating, it creates a hormone imbalance which can cause weight gain, diseases and other health issues.
Estrogen dominance can occur from birth control pills, use of hormone replacements, poor diet, smoking, alcohol use and stress which is associated with the adrenal gland, just to name a few.
Also, too much estrogen can possibly cause reoccurring bronchitis, severe allergies and asthma, heightened symptoms of menopause, severe PMS, headaches, irritability and infertility.
Estrogen is present in every organ in the body and utilized for many purposes. When there are higher levels of excessive bad estrogen, it stores in fat cells and it is difficult for the body to detoxify. If it remains there for excessive periods of time, it can cause risk for diseases, especially hormone related forms of cancer.
DIM’s effects on hormone balance for women are thought to improve symptoms of menopause, PMS and may even support weight loss. It also may be a preventative, reducing the risk of potential health issues and certain cancers that are related to estrogen imbalances.
Diindolylmethane (DIM) Side Effects & Dosage
Diindolylmethane seems to be likely safe when taken for a short period of time (12 weeks) in small dosages. It is important to follow the recommended dosage on the bottle.
When starting on any new Nootropic supplement, it is recommended to always take the lowest dose. This will help you determine how the Nootropic supplement will effect and/or benefit you and what dosage will work best for you.
Through the average dietary consumption of cruciferous vegetables such as broccoli, cauliflower and kale, we get approximately 2mg-20mg of DIM daily.
DIM can possibly be unsafe if it is used over a long period of time and with too high of a dosage. These cases were said to be caused by dosages higher than 600mg a day. Dosages of over 300mg per day may cause headaches and upset stomach.
DIM, is not recommended for pregnant or breast feeding women, people with hormone sensitive disorders, or people with cancer.
These are just guidelines. If you have any concerns or questions, speak to your doctor first before taking DIM.